Construction of Wild-type p53 Gene Recombinant Expression Vector and Its Antitumorigenic Effects on Human Colon Adenocarcinoma Cells
Article
Figures
Metrics
Preview PDF
Reference
Related
Cited by
Materials
Abstract:
p53 gene is a 16-20 kb of cellular DNA located on the short arm of human chromosome 17 at position 17pl3.1. This gene encodes a 393-amino acid nuclear phosphoprotein which involves in the regulation of cell proliferation. Loss of normal p53 function is as