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Archive > Volume 3 Issue 3 > 1996,3(3):211-213. DOI:10.3872/j.issn.1007-385X.1996.3.012 Prev Next

Preliminary Investigation on MHC-Nonrestricted Tumorlytic Effect Mediated by CD3AK

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    Abstract:
    The result showed that CD3AK induced and expanded in vitro could kill MHC I class - negative K562 (NK - sensitive) and Daudi (NK - resistant) tumor cells in a MHC - nonrestricted manner. Induction of necrosis and / or apoptosis of target cells were responsible for the tumorlytic effect mediated by CD3AK.

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