Tumor vaccines for breast cancer:challenges and opportunities
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Abstract:
Abstract Immunotherapy as a promising therapy strategy is expected to bring new hope for breast cancer treatment. Recently several breast cancer vaccines have been developed. Rational and rapid application of these scientific discoveries in clinical therapies for breast cancer patients poses great challenges and opportunities. This article is aimed to elaborate on the design strategies, current clinical trials, and future progression and application of breast cancer therapeutic vaccines. With the deepening of our understanding on the tumor-specific immune response and tumor microenvironment, and continuous discovery of new tumor-specific antigens, the research level of breast cancer vaccines will be further improved and will benefit the clinical treatment of breast cancer.
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Project supported by the Key Foundation from Science and Technology Commission of Tianjin (No.09jczdjc20400)