Mobile website
Archive > Volume 23 Issue 3 > 2016,23(3):318-325. DOI:10.3872/j.issn.1007-385X.2016.03.005 Prev Next
Expert Forum
The role of intestinal microbiota in cancer progression and advances of clinical researches
- Article
- Figures
- Metrics
- Preview PDF
- Reference
- Related
- Cited by
- Materials
Abstract:
Intestinal microbiota plays a critical role in regulating growth, development, nutrition and energy metabolism of a host, as well as immune homeostasis. Accumulating evidences had recently shown that the dysbiosis of the intestinal microbiota was frequently found in the patients with various cancers, especially with colorectal cancer. Alteration of the intestinal microbiota could improve or inhibit occurence and development of intestinal tumor through influencing metabolism, homeostasis and immune function of intestine. Currently, clinical practice of cancer therapy by intervene of the microbiota had shown good curative effects and a great potential. This review aims to discuss role of the intestinal microbiota on occurence and development of the intestinal tumor, and its mechanism, along with current progresses of clinical researches on treatment of the intestinal cancer with the intestinal microbiota.
Keywords:
Project Supported:
Project supported by the National Natural Science Foundation of China (No. 81571556，81273268，81500145), the Natural Science Foundation for Young Scholars of Jiangsu Province (No. BK201500352), and the China Postdoctoral Science Foundation (No. 7131702415)
Clc Number:
